血中PCO2変動時における血液・房水柵K移送に関して

K Transport across Blood-Aqueous Barrier Combined with the Alteration of Systemic Blood PCO2.

I．はじめに

　さきの報告に於いて，放射性Kを用いて，血液より新生房水へのturn over rateが血中の酸塩基平衡の変化によつて影響を受けることを報告した。

　即ち呼吸性，代謝性アチドージス共にKのturnoverを促進し，反対に呼吸性，代謝性アルカロージス共にKのturn overを抑制する。これは循環血中pH変動が遠位，末梢に於ける血液，新生房水間のK移送に影響をもつものとして興味深い事実である。

The turn over ratio of isotopic K from sys-temic blood to newly formed aqueous humour across blood-aqueous barrier in the anesthe-tized cat was studied. A trachectomy was perfomed and the cats were maintained on artificial respiration through the procedure.

PCO₂, pH, and K ratio (aqueous humour to serum) were checked with the lapse of time. PCO₂ was changed by hyperventilation, 5% CO₂ inhalation, transfusion of bicarbonate, and normal ventilation continuously. The K turn over across barrier seems to correspound directly to systemic blood pH, and not to systemic blood pCO₂.