ベーチェット病の眼病変における左右差と視力予後に関する検索

Bilaterality of ocular lesions and visual prognosis in Behçet disease

　ベーチェット病患者540例の眼病変の左右差について検討し，以下の結果を得た．

（1）1眼発症後2年以内に他眼に病変を発症した例は94.0％，5年以内では98.1％であった．性差については有意差はみられなかった．

（2）眼発症後2年間経過した後の虹彩毛様体炎型に留まる頻度は男性16.8％，女性35.7％であり，女性では虹彩毛様体炎型に留まる頻度は男性の2倍であった．全症例の約6％は1眼が虹彩毛様体炎型，他眼が網膜ぶどう膜炎型を呈した．

（3）予後不良とされている網膜ぶどう膜炎型を両眼に持つ症例の左右差について，視力と年間発作回数で新しい基準で検討した．視力に左右差の認められるのは眼発症後2年目で23,8％，5年目で28.5％，発作回数に左右差が認められるのは2年目で35.1％，5年目で15.8％であった．

We reviewed a consecutive series of 540 cases of Behçet disease with ocular lesions. We paid particular attention to the involvement of the second eye and its implication in the visual prognosis.

We could confirm that the second eye was involved within 2 years after the initial appearance of ocular lesions in the first eye in 94.0% of the cases. The second eye was involved within 5 years in 98.1% of the cases.

Iridocyclitis was the cardinal feature in 16.8% of male and in 35.7% of female patients two years after onset of ocular lesions.This type was generally associated with good visual prognosis. Iridocyclitis was present in oneeye and uveoretinitis in the other in 6% of cases in the present series.

A total of 389 cases manifested bilateral uveoretinitis type of the disease. The severity of ocular lesions was not necessarily the same in this group. Judging by our new criteria about unequality between both eyes, considerable錨ifference in visual acuity between both eyes was present in 28.5% of the cases at 5 years afterocular onset and in 30.2% at 10 years.

Rinsho Ganka (Jpn J Clin Ophthalmol) 40(5) : 469-472, 1986