先天小瞳孔に白内障を伴う菲薄水晶体と緑内障を合併した2症例

Two cases of congenital microcoria with cataract, thinning of crystalline lens and glaucoma

要約　目的：白内障，菲薄化した水晶体，緑内障が併発した先天小瞳孔の2症例の報告。症例：それぞれ生後3か月と7か月の男児が眼振と角膜混濁で受診した。両眼にそれぞれ瞳孔径0.2mmと0.5mmの小瞳孔があり，白内障と菲薄化した水晶体があった。水晶体摘出術と瞳孔形成術を両症例に行った。1例では以後眼圧が上昇したが，点眼加療で11年後の現在まで眼圧は正常化している。他の1例には発達異常緑内障の併発があり，線維柱帯切除術を行い，14か月後の現在まで眼圧は正常化している。結論：先天小瞳孔では，白内障，菲薄化した水晶体，緑内障が併発することがある。

Abstract.　Purpose：To report 2 cases of microcoria associated with cataract, thinning of the lens, and glaucoma. Cases：Both were male infants presented with nystagmus and opaque cornea. They were aged 3 and 7 months respectively. Both cases showed microcoria in both eyes with pupillary diameter of 0.2 and 0.7 mm each. They also showed cataract and thinning of the lens. Both cases were treated by lens extraction and pupilloplasty. Elevated intraocular pressure（IOP）in one case was controlled by topical medication for 11 years until present. The other case showed developmental glaucoma. IOP has been controlled after trabeculectomy for 14 months until present. Conclusion：These cases illustrate that microcoria may be associated with cataract, thinning of the lens, and glaucoma.