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A case suspected of ethambutol optic neuritis Hiromi Fukuda 1 , Yoko Okubo 1 , Hideo Mori 1 1Dept of Ophthalmol,Osaka City Gen Hosp pp.375-380
Published Date 2011/3/15
DOI https://doi.org/10.11477/mf.1410103587
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Abstract. Purpose:To report a case of bilateral optic neuropathy following peroral treatment with ethambutol. Case:A 71-year-old female was referred from an internist. She had been diagnosed with rheumatoid arthritis followed by treatment with corticosteroid and immunosuppressive agents. She started receiving antibiotics for nontuberculous pneumonitis since 8 years before. Findings:Her corrected visual acuity was 0.6 right and 1.2 left. The right eye showed macular degeneration. She immediately started receiving systemic treatment including ethambutol. She developed numbness in the lower extremities 2 months later. She noted impaired vision 7 months after start of ethambutol with visual acuity of 0.09 right and hand motion left. Both eyes showed central scotoma suggestive of retrobulbar optic neuropathy. Visual acuity improved to 0.15 right and 0.04 left 18 months after her initial visit. Conclusion:There is a high possibility that systemic ethambutol was involved in the causation of optic neuropathy in the present case.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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