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要約 目的:ヒト免疫不全ウイルス感染者の眼症状の検討。対象と方法:2005年までの41か月間に眼科を受診した500例を診療録により調査した。結果:年齢は10~82歳(平均37.4歳)であり,男性が91%,女性が9%であった。初診時のCD4陽性リンパ球数は200/μl未満が48.3%であった。眼病変は146例(29.2%),237眼(部位)(23.7%)にあり,retinal microvasculopathyが最も多く,サイトメガロウイルス網膜炎,免疫再構築症候群がこれに続いた。結論:ヒト免疫不全ウイルス感染に対して多剤併用療法が主流になっている現在でも,眼病変の発症があり注意が必要である。
Abstract. Purpose:To evaluate ocular manifestations in persons infected by human immunodeficiency virus(HIV). Cases and Method:This retrospective study was made on 500 persons who were referred to the Department of Ophthalmology for HIV during 41 months through 2005. Results:The series comprised 455 males(91.0%)and 45 females(9.0%). The age ranged from 10 to 82 years, average 37.4 years. The number of CD4+ lymphocytes in the circulating blood was less than 200/μl in 48.3% of cases. Ocular lesions were present in 146 cases(29.2%)and in 237 eyes(region)(23.7%). Retinal microvasculopathy was the most frequent and was followed by cytomegalovirus retinitis and immune reconstitution syndrome. Conclusion:Ocular involvement is still frequent in the current age of highly active antiretroviral therapy(HAART).
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