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要約 目的:ヒト免疫不全ウイルス(HIV)網膜症でのCD4陽性Tリンパ球数と血漿中HIV RNA量の報告。対象と方法:HIV網膜症と診断された105例163眼につき,CD4数とHIV RNA量を診療録で検索した。結果:163眼中149眼(91.3%)ではCD4数が200/μl未満であり,これ以上の14眼中13眼ではHIV RNA量が2.1×104コピー/ml以上であった。163眼中144眼(88.3%)ではHIV RNA量が1×104コピー/ml以上であり,これ未満の19眼中16眼ではCD4数が200/μl未満であった。結論:HIV網膜症が発症した眼の多くでは,CD4陽性Tリンパ球が少なく,血漿中HIV RNA量が高い。
Abstract. Purpose:To report the CD4-positive T-lymphocyte count and serum HIV RNA level in patients with HIV retinopathy. Cases and Method:This retrospective study was made on 163 eyes of 105 patients who were diagnosed with HIV retinopathy. Results:Out of 163 eyes,CD4-positive T-lymphocyte count was less than 200/μl in 149 eyes(91.3%). In 13 out of 14 eyes that showed higher CD4 count,HIV RNA level was 2.1×104 copies/ml or higher. Out of 163 eyes,144 eyes(88.3%)showed HIV RNA level of 1×104 copies/ml or higher. In 16 out of 19 eyes that showed lower levels,CD4 count was less than 200/μl. Conclusion:In the majority of eyes with HIV retinopathy,CD4-positive T-lymphocyte count is decreased and serum HIV RNA level is elevated.
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