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Japanese

Vimentin and Desmin Expression in the Type 2 Fibers in Muscle Biopsies from Myotonic Dystrophy Patients Kimiaki Utsugisawa 1 , Munehisa Yamagata 1 , Hisasi Yonezawa 1 , Satoshi Takahasi 1 , Hideo Tohgi 1 1Department of Neurology, Iwate Medical University Keyword: myotonic dystrophy , vimentin , desmin , type 2 fiber , regeneration pp.245-249
Published Date 1995/3/1
DOI https://doi.org/10.11477/mf.1406900759
  • Abstract
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Immunoreactivity for the intermediate filament proteins vimentin and desmin was assessed in the type 2 fibers of biceps brachii muscle biopsies from 20 adults with myotonic dystrophy (MD). Some type 2C fibers showed strong reactivity with both anti-vimentin and anti-desmin, suggesting that they were regenerating fibers. Some type 2A and 2B fibers of various diameter were weakly reactive with anti-vimentin, but none of the type 1 fibers were reactive with anti-vimentin.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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