調節呼吸の研究（2）

Studies on controlled respiration (Part 2)

IV．コンプライアンスよりの分析

　自然呼吸と調節呼吸とでは換気力学的機構は自ら異つている。外科手術の発達と共に，筋弛緩剤を用いて調節呼吸を行うことは一般に広く行われているところである。麻酔時，適正換気を目ざす場合，果して自然呼吸時と同じ考えで調節呼吸を行つていいものか，又は異つた機構になるかを比較検討し，適正換気を得る為の指標を追求した。

Problms of controlled respiration in general anesthesia were studied.

The study was divided into the four.

1. CO₂-homeostasis in spontaneous respiration.

2. Alveolar ventilation.

3. Ventilation-perfusion relationships in open chest surgery.

4. The mechanics of ventilation.

The following results weres obtained

1. During spontaneous respiration CO₂-homeostasis was disturbed by some anesthetic agents.

2. Then controlled respiration was necessary concerning the alvealar ventilation. But the difference between them was not found. But when we thought the dead space ventilation and alveolar ventila- tion, the anesthesic apparatus gave the another important factor.

3. In open chest procedure, the ventilation-perfusion relationship was inproved by controlled respiration.

4. The static and dynamic compliance during controlled resiration was measured. The patient's position, the site of operation influened the value of compliance.

The compliance in controlled respiration was decreased than that of spontanenous respiration.

The FRC was not significantly changed under controlled respiration

It was imporant under conrolled respiration that the change of compliance should be considered and not the tidal ventilation but should the alveolar ventilation be the principal purpose.