Epstein-Barr Virus-Associated Carcinoma and Lymphoma of the Stomach Yasuharu Kaizaki 1 1Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan Keyword: Epstein-Barrウイルス , EBV , 潜伏感染 , 胃癌 , 悪性リンパ腫 , 免疫不全状態 pp.1667-1674
Published Date 2019/11/25
DOI https://doi.org/10.11477/mf.1403201892
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 EBV(Epstein-Barr virus), a member of the herpes virus family, infects most of the adult population latently. EBV infection has been associated with the pathogenesis and tumor progression of various malignant neoplasms. The histologic types that form a mass in the stomach are EBV-associated gastric carcinoma, EBV-positive diffuse large B-cell lymphoma, other non-specified, extranodal NK/T cell lymphoma, nasal type, chronic active EBV infection, and immunodeficiency-associated lymphoproliferative disorders. EBV-associated gastric carcinoma has a special form of carcinoma with lymphoid stroma, which contributes to a good prognosis. Most EBV-associated lymphomas are caused by immunodeficiencies. They are macroscopically and histologically atypical and are difficult to diagnose. It is necessary to understand their pathogenesis.

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