Endoscopic Evaluation of Disease Severity in Crohn's Disease:Usefulness and Problems of Scoring System Using Ileocolonoscopy Yuta Fuyuno 1 , Yutaka Nagata 1 , Yasuharu Okamoto 1 , Atsushi Hirano 1 , Junji Umeno 1 , Takehiro Torisu 1 , Tomohiko Moriyama 1 , Motohiro Esaki 1 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Keyword: Crohn病 , 粘膜治癒 , CDEIS , SES-CD pp.194-202
Published Date 2018/2/25
DOI https://doi.org/10.11477/mf.1403201285
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 We retrospectively investigated the clinical usefulness of SES-CD(simple endoscopic score for Crohn's disease)for predicting the loss of response to an anti-TNF-a antibody therapy in patients with Crohn's disease who subsequently achieved clinical remission and whose clinical course after endoscopic evaluation could be followed up for >1 year. A significantly higher recurrence rate was observed in patients with SES-CD of >10 than in those with SES-CD of 10. In contrast, no difference existed between patients with ulceration(>5mm)and those without ulceration with respect to the recurrence rate. Although further prospectively designed studies with a larger number of cases are necessary, SES-CD appears to be useful for predicting the loss of response to the anti-TNF-a therapy.

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