Diagnosis and Management of Small Hemorrhagic and Non-tumorous Intestinal Diseases:Miscellaneous Diseases Motohiro Esaki 1 , Takehiro Torisu 1 , Junji Umeno 1 , Atsushi Hirano 1 , Yasuharu Okamoto 1 , Yuta Fuyuno 1 , Yuji Maehata 2 , Shinichi Kawano 1 , Keizo Zeze 1 , Akira Harada 1 , Yoshifumi Hori 3 , Minako Fujiwara 3 , Takayuki Matsumoto 4 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Maehata Clinic, Kagoshima, Japan 3Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 4Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan Keyword: 血管炎症候群 , 非特異性多発性小腸潰瘍症 , 腸管Behçet病 , 小腸出血 pp.838-846
Published Date 2018/5/25
DOI https://doi.org/10.11477/mf.1403201387
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 We reviewed inflammatory disorders that can cause multiple small intestinal ulcers, including vasculitis syndrome, CEAS(chronic enteropathy associated with SLCO2A1 gene), and intestinal Behçet's disease. Although endoscopic procedures are crucial for the diagnosis of such diseases, radiographic investigation is more useful than endoscopy for the evaluation of distribution and localization of small bowel mucosal lesions. In addition, radiology offers more information for differential diagnoses compared with endoscopic observations. Endoscopic balloon dilation is useful for the treatment of intestinal strictures of CEAS. However, since many small intestinal ulcers caused by diseases are usually treated by medications such as systemic steroids, immunomodulators, and biologics, interventional endoscopic hemostasis is rarely applied in the management of these conditions.

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