Evaluation of the Severity of Ulcerative Colitis Using Endocytoscopy Yoshihiro Nakazato 1 , Rieko Bessho 2 , Naoki Hosoe 1 , Makoto Naganuma 3 , Haruhiko Ogata 1 1Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo 2Center for Preventive Medicine, Keio University School of Medicine, Tokyo 3Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo Keyword: 超拡大内視鏡 , endocytoscopy , endocytoscopy system score , 潰瘍性大腸炎 pp.183-192
Published Date 2018/2/25
DOI https://doi.org/10.11477/mf.1403201283
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 Conventional endoscopy is useful for long-term prognosis in UC(ulcerative colitis). However, recently, histological remission is thought to be more important than endoscopic remission. Although a biopsy is required to assess the histological severity of colitis, it can only assess a limited area. In addition, biopsies are associated with a risk of bleeding and, in rare cases, perforation. In recent years, ECS(endocytoscopy)has emerged as a new technique. ECS enables magnification up to 450 times and allows for the observation of crypts. We reported an ECSS(ECS score)to determine the histopathological activity index of UC and confirmed that the ECSS is strongly correlated with histological severity. Additionally, ECSS can also assess histological severity in endoscopic remission. ECS may be a useful monitoring tool for predicting relapse.

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