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Endoscopic and Radiographic Features of Colonic Tuberculosis Yuji Maehata 1 , Motohiro Esaki 1 , Shuji Kochi 2 , Hiroki Yaita 3 , Hyonji Kim 4 , Shin Fujioka 5 , Koji Ikegami 6 , Yutaro Ihara 7 , Daisuke Akiyoshi 8 , Risa Hida 9 , Minako Hirahashi 9 , Yutaka Nagata 1 , Yasuharu Okamoto 1 , Tomohiko Moriyama 1 , Takayuki Matsumoto 10 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Chihaya Hospital, Fukuoka, Japan 3Matsuyama Red Cross Hospital, Matsuyama, Japan 4Fukuoka Yutaka Central Hospital, Nogata, Japan 5Fukuoka Red Cross Hospital, Fukuoka, Japan 6Kyushu Hospital, Kitakyushu, Japan 7Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan 8Fukuoka Sanno Hospital, Fukuoka, Japan 9Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 10Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan Keyword: 大腸結核 , 輪状潰瘍 , 不整形潰瘍 , 肉芽腫 , IFN-γ遊離試験 pp.169-179
Published Date 2017/2/25
DOI https://doi.org/10.11477/mf.1403200831
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 We investigated the clinicopathological features of 54 patients with colonic tuberculosis. Of these patients, 42(44%)did not manifest any clinical symptoms. Colonic invasion was found mostly in the cecum(75%)and in the ascending colon(74%). The most frequently observed active mucosal lesions in colonoscopy and radiography included irregular ulcers(63%), circular ulcers(56%), and erosions(50%). Although 80% of patients were accompanied by colonic deformity or discolored multiple scars suggesting chronic inflammatory change, mild mucosal lesions were observed in 11% of patients. In the analyses of biopsy specimens, while epithelioid cell granuloma with caseous necrosis was observed only in 15% of patients, the detection rate of acid-fast bacilli was highest in culture(48%). Based on our findings, interferon-gamma release assay may be necessary to diagnose colonic tuberculosis if the disease is suspected in radiography or colonoscopy.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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