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要旨 寛解期潰瘍性大腸炎における潰瘍性大腸炎関連腫瘍(UCAN)と散発性腫瘍(SCA)の注腸X線造影所見を比較した.UCAN 15病変は9病変が表面型,6病変が隆起型であった.一方,SCA 6病変は表面型が4病変,隆起型が2病変であった.表面型を呈したUCANとSCAのそれぞれ2病変でバリウム斑を有していた.表面型UCANでは9病変のうち7病変で病変境界が不明瞭であったのに対し,表面型SCAでは4病変とも明瞭な病変境界を有していた(p=0.02).一方,隆起型腫瘍ではUCANはSCAに比べて隆起の大小不同が顕著であった.以上より,早期病変におけるUCANとSCAの鑑別には,X線造影像における病変境界所見と隆起の大小不同に着目することが有用と考えられた.
We retrospectively compared the radiographic findings of colitis-associated neoplasia with sporadic cancer/adenoma in patients with ulcerative colitis. Morphologically, colitis-associated neoplasia was classified into flat elevated lesions(n=8)or protruding lesions(n=7). Sporadic cancer/adenoma was also classified into flat elevated lesions(n=4)and protruding lesions(n=2). Of the 12 flat elevated lesions, all 4 sporadic cancer/adenomas were clearly demarcated on radiography, whereas such radiographic characteristics were found in only 2 of the 8 colitis-associated neoplasias(p=0.06). Radiographically, most of the protruding colitis-associated neoplasias appeared as irregular masses composed of nodules of various sizes. Although further investigation should be mandatory, vague demarcation and obvious inequality of nodules on radiography may allow the differentiation of colitis-associated neoplasia from sporadic cancer/adenoma in patients with ulcerative colitis.
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