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Gastrointestinal Manifestations in Systemic Lupus Erythematosus Yuji Maehata 1 , Motohiro Esaki 1 , Koichi Asano 1 , Junji Umeno 1 , Takehiro Torisu 1 , Tomohiko Moriyama 1 , Kakuya Amano 2 , Shotaro Nakamura 3 , Risa Hida 4 , Yoshiteru Kumagae 4 , Minako Hirahashi 5 , Takanari Kitazono 1 , Takayuki Matsumoto 3 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Sakura Hospital, Fukuoka, Japan 3Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan 4Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 5Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan Keyword: 全身性エリテマトーデス , SLE , ループス腸炎 , 虚血性腸炎型 , 多発潰瘍型 , 蛋白漏出性胃腸症 , PLE pp.1397-1405
Published Date 2015/10/25
DOI https://doi.org/10.11477/mf.1403200448
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 Intestinal lesions in SLE(systemic lupus erythematosus)are classified into protein-losing enteropathy and lupus enteritis, which is subdivided into the ischemic enteritis type and multiple ulcer type. The ischemic enteritis type is characterized by diffuse submucosal edema in the small bowel. In protein-losing enteropathy, endoscopic examination usually reveals minimal abnormalities, although erosions or small ulcers are occasionally observed. The multiple ulcer type is characterized by multiple punched-out ulcers found in the distal colon, and they often cause intestinal perforation. In addition, cases of gastroduodenal ulcer caused by vasculitis have been reported. Intestinal lesions can develop as the initial presentation of SLE and severe complications such as intestinal perforation may occur. Thus, intestinal lesions in SLE should be assessed at the initial diagnosis and during the follow-up.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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