Japanese

Eosinophilic Granulomatosis with Polyangiitis(Churg-Strauss Syndrome) Yasuharu Okamoto 1,2 , Koichi Kurahara 1 , Motohiro Esaki 2 , Miyuki Sawano 2 , Junji Umeno 2 , Yuji Maehata 2 , Shuji Kochi 2 , Yumi Oshiro 3 , Risa Hida 4 , Yoshiteru Kumagae 4 , Minako Hirahashi 5 , Keisuke Kawasaki 6 , Shotaro Nakamura 6 , Takayuki Matsumoto 6 , Tadahiko Fuchigami 1 1Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan 2Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 3Division of Pathology, Matsuyama Red Cross Hospital, Matsuyama, Japan 4Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 5Department of Health Science, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan 6Division of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan Keyword: 好酸球性多発血管炎性肉芽腫症 , Churg-Strauss症候群 , EGPA , ANCA関連血管炎 , 消化管病変 pp.1372-1380
Published Date 2015/10/25
DOI https://doi.org/10.11477/mf.1403200445
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 To determine the characteristics of GI(gastrointestinal)involvements in patients with EGPA(eosinophilic granulomatosis with polyangiitis), we reviewed the findings of GI examinations in 10 such patients. The 10 patients included 7 men and 3 women, with an average age of 53.2 years. GI involvements were found in the duodenum in 2, jejunum or ileum in 2, terminal ileum in 1, and colorectum in all patients. Colorectal involvements were more frequent in the distal colorectum than in the proximal colon(p=0.015). Multiple erosions or ulcerations accompanied by marginal reddish mucosa were considered to be the characteristic GI findings. Distal colorectum was the most frequently involved site in EGPA. Small intestine seems to be frequently involved in the disease ; however, further investigation is necessary.


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