Japanese

Histopathologic Characteristics of Superficial Adenocarcinoma in Barrett's Esophagus in Japan Hiroshi Kawachi 1 , Tomoki Shimizu 2 , Manabu Takamatsu 1 , Noriko Yamamoto 1 , Maki Kobayashi 1 , Junko Fujisaki 2 , Yuichi Ishikawa 1 1Department of Pathology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo 2Department of Endoscopy, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo Keyword: Barrett esophagus , adenocarcinoma , dysplasia , pathology , diagnosis pp.1259-1268
Published Date 2016/9/25
DOI https://doi.org/10.11477/mf.1403200723
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 The pathologic characteristics of superficial adenocarcinoma in Barrett's esophagus were analyzed in 36 consecutive cases from The Cancer Institute Hospital of the Japanese Foundation for Cancer Research. The protruding or slightly elevated type was more frequent than the flat or slightly depressed type. For the evaluation of the extent of invasion, identification of a double muscularis mucosa was important, although it was occasionally difficult. Regarding tumor differentiation, a majority of cases contained well-to-moderately differentiated components in the mucosa and poorly differentiated components in the submucosa.“Barrett's cancer under the squamous epithelium”was frequently observed. In this study, more than 90% of the cases had SSBE(short segment Barrett's esophagus)in the background mucosa, and LSBE(long segment Barrett's esophagus)was infrequent. Lymph node metastasis was found only in one case. When comparing these findings with those from Western countries, the differences in the histopathologic diagnostic criteria, the prevalence of SSBE/LSBE, and the surveillance methods need to be considered.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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