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Epidemiology of Barrett's Esophageal Cancer Takayuki Nishi 1 , Hideo Shimada 1 , Takayuki Tajima 1 , Tomoki Nakamura 1 , Hiroshi Miyakita 1 , Takashi Ohgimi 1 , Osamu Chino 2 , Tomoko Hanashi 2 , Yasushi Yamazaki 2 , Soichiro Yamamoto 3 , Shuji Uda 3 , Junya Oguma 4 , Akihito Kazuno 4 , Miho Nitta 4 , Yamato Ninomiya 4 , Hirohito Miyako 4 , Soji Ozawa 4 , Hiroyasu Makuuchi 5 1Department of Surgery, Tokai University Oiso Hospital, Kanagawa, Japan 2Department of Surgery, Tokai University Tokyo Hospital, Tokyo 3Department of Surgery, Tokai University Hachioji Hospital, Hachioji, Japan 4Department of Surgery, Tokai University School of Medicine, Isehara, Japan 5Tokai University Hospital, Isehara, Japan Keyword: Barrett食道癌 , 食道腺癌 , 逆流性食道炎 , 疫学 , 頻度 pp.1252-1258
Published Date 2016/9/25
DOI https://doi.org/10.11477/mf.1403200722
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 Over the past decades, the incidence of esophageal adenocarcinoma has rapidly increased in the US and Europe. In Japan, the incidence of esophageal adenocarcinoma was approximately 2.0% of the population until 1999, and this increased to 6.4% by 2013. Several investigations have identified white race, male sex, GERD, obesity, and the absence of Helicobacter pylori status as risk factors for esophageal adenocarcinoma. It is recognized that the prevalence of obesity and the frequency of GERD are much lower in the Japanese population compared with those in the US and Europe. Therefore, the incidence of Barrett's adenocarcinoma in Japan is unlikely to increase as dramatically as that in the Western countries.


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