消化管ポリポーシスにおける上部消化管病変の特徴

The Characteristic of the Upper Gastrointestinal Lesions of Systemic Disease, Alimentary Tract Polyposis

要旨　消化管ポリポーシスという疾患群は，しばしば上部消化管病変の発見が診断の契機となる．そこでCowden病，大腸腺腫症，Turcot症候群，Peutz-Jeghers症候群，若年性ポリポーシス，Cronkhite-Canada症候群について，上部消化管病変を口腔内，食道，胃・十二指腸に分け，病変の有無とその形態学的な特徴像について述べた．食道ポリポーシスは，Cowden病に特徴的な所見であった．消化管ポリポーシスで認められる胃・十二指腸病変を，病変の分布，大きさ，形態，均一性の有無，大小不同の有無，ひだとの関係で検討し，鑑別診断に至る過程を論じた．

　Detection of upper gastrointestinal (GI) lesions may lead to diagnosis of gastrointestinal polyposis. Upper GI lesions of Cowden's isease, adenomatosis coli, Turcot syndrome, Peutz-Jeghers syndrome, Juvenile polyposis, Cronkhite-Canada syndorome were stratified by location (oral cavity, esophagus, gastroduodenum), and their location and morphological characteristics were described.

　Esophageal polyposis was specific to Cowden's disease. Gastroduodenal lesions of gastrointestinal polyposis were evaluated in terms of distribution, size, shape, uniformity, irregularity in size of the lesions, and their relation to mucosal folds, then differential diagnosis were discussed.