Radiological and Endoscopic Features of Upper Gastrointestinal Lesions in Patients with ATL and Schönlein-Henoch Purpura Shin-ichiro Aozaki 1 , Fujio Hamada 1 , Yasutada Baba 1 1Division of Internal Medicine, Saiseikai Sendai Hospital Keyword: 血液疾患 , 上部消化管病変 , 成人T細胞白血病 , Schönlein-Hencch紫斑病 pp.1377-1388
Published Date 1994/12/25
DOI https://doi.org/10.11477/mf.1403106016
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 Digestive symptoms are rare as the first symptoms of blood diseases. However, it is not the case in patients with adult T-cell leukemia (ATL).ATL is often found with complaints of digestive symptoms.

 We demonstrated radiological, endoscopic and pathological findings of the upper gastrointestinal (GI)lesions in six patients with ATL who had digestive symptoms at the onset of the disease, and then tried to illustrate these findings by discussing other reported findings.

 Although esophageal involvement was proved in autopsied materials, neither radiological nor endoscopic examinations were useful to detect the lesions in ATL patients. As far as we know, there have been no reports that esophageal involvement was found by these methods.

 In our study, gastric lesions in ATI. patients were macroscopically similar tothose in patients with systemic malignant lymphoma or primary gastric malignant lymphoma. The results were consistent with other reported cases. There was one report that showed the gastric mucosal lesion which was composed of multiple aggregated nodules.

 Duodenal lesions were macroscopically found to assume the form of multiple nodules with several central depressions.

 These results suggest that ATL should also count as one of the possible differential diagnoses when we recognize malignant lymphoma by radiological or endoscopic examinations in the upper GI tract.

 We added radiological and endoscopic findings of the upper GI tract in two patients with Shönlein-Henoch purpura, an allergic disease. They had complained of severe abdominal symptoms.

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