—北村教授開講十周年記念論文—鼻粘膜炎症と体質をめぐる問題（その3）

　まえがき

　われわれは慢性副鼻腔炎に下甲介の肥厚を伴うもの（E）と萎縮を伴うもの（A_2）を対比しながら鼻粘膜炎症反応に及ぼす体質の影響を検討した。すなわちいろいろの体質学的検査を行い，更にその検査成績に影響をもつと考えられる諸因子を検討し，内分泌機能異常が検査成績，粘膜反応型の説明に最も都合がよいであろうという結論を得た。そこで鼻炎症と内分泌機能の関係を更に確めるため内分泌異常者の鼻所見を検し，又内分泌異常がいかにして鼻粘膜炎症に関与するかについて二三の実験を行つた。そして内分泌体質学の立場から鼻粘膜の炎症を観察した。

From the standpoint of Pn characteristic changes will be manifested both in the adults as Well as the children according to the type of abnormality that involves the internal Secre-tion.Pneumatization was found to be supp-ressed with functional lowering of activities in the various organs such as,sex glands, adrenal cortex and the thyroids.When DOCA was administered to experimental rhino-sinu-sitis a typical increase was seen in the po-lypoid tissue growth on the nasal mucous membrane and this growth could be controled with increase or decrease by the amount of internal secretion made available.That, when the amount of internal secretion was altered during pregnancy the Pn and vulnerbility to nasal infection in the sibling was definitely effected, was estblished by clinical animal experimentation.The Pn and vulnerbility to nasal infections were found to be defini-tely controled by internal secretions both pre and postnatally.