雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

MAGNETIC RESONANCE IMAGING IN OPTIC NERVE LESIONS WITH MULTIPLE SCLEROSIS Shigeyuki Kojima 1 , Keizo Hirayama 1 , Yonetsugu Kakisu 2 , Emiko Adachi 2 1Department of Neurology, School of Medicine, Chiba University 2Department of Ophthalmology, School of Medicine, Chiba University Keyword: optic neuritis , multiple sclerosis , magnetic resonance imaging , short inversion time inversion recovery(STIR) pp.1191-1195
Published Date 1990/12/1
DOI https://doi.org/10.11477/mf.1406900139

閲覧方法のご案内

この論文を閲覧するためにはログインが必要になります。
パスワードを忘れた場合 新しくユーザー登録する 施設共通IDをご利用の方はこちらから

PPV購入案内

1,320円 (1,200円+税10%) こちらは、1191ページから1195ページの文献です。
PPV(ペイ・パー・ビュー)とは、論文(記事)単位で購入・閲覧ができるサービスです。
購入には医書.jp本会員登録が必要です。



会員登録完了後に改めて上記「購入サイトへ」を選択してください。
または「購入サイトへ」選択後に「購入ログイン」、「新規会員登録」の順に進んでください。

会員登録について詳しくはをご確認ください。
  • Abstract
  • Look Inside

Magnetic resonance imaging (MRI) of the optic nerves was performed in 10 patients with multiple sclerosis (MS) using short inversion time inversion recovery (STIR) pulse sequences, and the results were compared with the visual evoked potentials (VEP).

The 10 patients had optic neuritis in the chronic or remitting phase together with additional symp-toms or signs allowing a diagnosis of clinically definite or probable MS. Sixteen optic nerves were clinically affected and 4 were unaffected. MRI was performed using a 0.5 tesla supercon-ducting unit, and multiple continuous 5 mm coronal and axial STIR images were obtained. A lesion was judged to be present if a focal or diffuse area of increased signal intensity was detected in the optic nerve. In VEP, a delay in peak latency or no P 100 component was judged to be abnormal.

With regard to the clinically affected optic ner-ves, MRI revealed a region of increased signal in-tensity in 14/16 (88%) and the VEP was abnormal in 16/16 (100%). In the clinically unaffected optic nerves, MRI revealed an increased signal intensity in 2/4 (50%). One of these nerves had an abnor-mal VEP and the other had a VEP latency at the upper limit of normal. The VEP was abnormal in 1/4 (25%). In the clinically affected optic nerves, the degree of loss of visual acuity was not associ-ated with the longitudinal extent of the lesions shown by MRI. The mean length was 17.5 mm in optic nerves with a slight disturbance of visual acuity and 15.0 mm in nerves with severe visual loss.

MRI using STIR pulse sequences was found to be almost as sensitive as VEP in detecting both clini-cally affected and unaffected optic nerve lesions in patients with MS, and was useful in visualizing the location or size of the lesions.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

関連文献

もっと見る

文献を共有