頭蓋内黒色腫を伴つたMélanoses neurocutanées Touraineの1例

A Case of Mélanoses nouro-cutanées Touraine with Intracranial melanoma

　大脳に於ける変化が，その他の身体部位に於ける異常と対応する如く存在する事がある。即ち，体の先天性異常，一種の奇型と言わるべきものと，脳の特殊なる疾患とが併存する症例は，時々我々の経験する所である。

　我々は，比較的稀とせられる頭蓋内黒色腫が，？幹の広範囲に及ぶ先天性色素性母斑を有する患者に於いて発見せられ，Mélanoses neuro-cuta-nées Touraineに入れらるべきもので，頭蓋内の一部に於いて，Melanom化を伴つたものと考えられるので報告する。

We have experienced a case of intracranial melanoma, occured in an 21 year-old man, who had congenitaly a wide distributed pigmented moles on the chest and back, as if he weared a black waistcoat, and smaller ones were found on the head, arms and legs.

On the clinical examinations we could not notice the character of brain tumor, and the patient died after a pneumoventriculographic examination.

At autopsy it was discoverd that the black tumor, 6.0×4.5×5.0cm insize, was located in the left temporal tip and was localized shar-ply from the brain substance, and moreover several black spots were found on the cerebral and cerebellar surface.

Microscopically, the tumor contained many round polygonal nervus cells together with a few spindle cells together with a few spindle cells. The cytoplasm of nervus cells was quite large and the nuclei was bright which has numerous mitotic figures. The pigment was assumed to be of the character of melanine, since of failed to give an ironreaction with appropiate microchemieal tests.

The black spots on cerebral and cerebellar surface were not malignant figures.