BENIGN ACANTHOSIS NIGRICANS ACCOMPANIED WITH OBESITY Kikuo MINAMI 1 , Masaaki TASHIRO 1 , Sumio KOURA 1 1Department of Dermatology, Faculty of Medicine, Kagoshima University pp.55-60
Published Date 1968/1/1
DOI https://doi.org/10.11477/mf.1412200272
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A 14-year-old girl had had a tendency to besity since 5 years which was accompanied with dark brown pigmentation around the neck. Three years ago, the pigmented lesions were also found in the axillary, genito-femoral, inframammary, intermammary and popliteal regions symmetrically. At her first visit, the patient was obese, with body weight of 77kg. The fat was deposited evenly on the trunk and extremities. In the cervical, axillary, inframammary, intermammary, genito-femoral, cubital and popliteal regions there were dark brown papillary lesions with pronounced lichenification.

Histologic specimen showed marked hyperkeratosis and papillomatosis with elongation of the papillae, slight acanthosis and partial melanization in the basal cell layer.

Laboratory tests revealed diabetes mellitus and hypertension.

Influence of reducement of the body weight on the skin manifestations is to be followed up and to be reported.

Copyright © 1968, Igaku-Shoin Ltd. All rights reserved.


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