有毛性巨大母斑を伴つた原発性軟脳膜黒色腫について—1剖検例

ON THE CASES OF PRIMARY LEPTOMENINGEAL MALIGMANT MELANOMA:An autopsy case

I．はじめに

　黒色腫の原発部位としては，中枢神経系は比較的まれであるが，発生部位別頻度からすれば，皮膚，眼球に相次いでいる^17）。

　中枢神経系原発性黒色腫はVirchow （1859）が最初に報告し，その後相次いで報告されたが，往々にして母斑を伴うことをTouraine （1949）^29）が認め，その一群をmelanose neuroctaneeと呼ぶことを提唱した。

1. An autopsy case of primary leptomeningeal malignant melanoma with giant hairy nevi, 29 year old woman, is reported.

2. Comparing the age at onset between Japanese and foreign cases of primary CNS melanoma with nevi, the distribution of the onset age of foreign case shows two phasic curve and about as half of them belong to less than one year, while the curve of Japanese cases distribute scattery.

In other word, the onset age of Japanese case ex-traordinary delayed the white cases.

We think this tendency seem to be one of pro-minent feature of Japanese brain tumor.

3. There is no difference between CNS primary melanoma with hairy nevi and with non-hairy nevi, in their age at onset and clinical prognosis.