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Radical hysterectomy for patients with adenocarcinoma of the uterine cervix:clinical trial JCOG1101 and JCOG1402 Takahiro Kasamatsu 1 1Department of Obstetrics and Gynecology Tokyo Metropolitan Bokutoh Hospital Keyword: 子宮頸部腺癌 , 広汎子宮全摘術 , 神経因性膀胱機能障害 , 術後照射 pp.863-870
Published Date 2018/8/10
DOI https://doi.org/10.18888/rp.0000000514
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Radical hysterectomy followed by adjuvant radiotherapy is widely accepted as the standard surgical procedure for patients with FIGO stageⅠB-ⅡB adenocarcinoma of the uterine cervix. In our retrospective study, there was no significant difference in survival or relapse, after adjusting for other clinicopathological characteristics, between the adenocarcinoma and squamous cell carcinoma at any pathological stage. However, surgical damage to the pelvic autonomic nerve can occur after the wide resection of parametrial and paravaginal tissue causing long-term severe neurogenic bladder, whereby patients are unable to empty their bladder and suffer a loss of the sense of urgency to void after surgery. The Japanese Clinical Oncology Group study 1101(JCOG 1101)is a multi-institutional non-randomized confirmatory PhaseⅢ trial to evaluate the efficacy of non-radical hysterectomy without bladder dysfunction for patients with tumor diameter ≤2cm with FIGO stageⅠB1 uterine cervical cancer confirmed by magnetic resonance imaging(MRI)before surgery in comparison with radical hysterectomy.


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電子版ISSN 印刷版ISSN 0009-9252 金原出版

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