Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
さまざまな病態を背景とした急性腎障害(AKI)に関して研究が進み,古典的な腎前性/腎性/腎後性という分類とは異なるアプローチが求められるようになっている。ICU・救急外来におけるAKIの特徴と,心腎連関,敗血症性AKI,心臓手術関連AKI,肝腎症候群,腹部コンパートメント症候群に伴うAKIを取り上げその機序や治療法を概説する。どの病態も血行動態,神経体液性因子の異常,炎症や代謝,薬物などが複雑に関与し,多角的な管理が必要と考えられる。腎代替療法では近年,個々の病態やdialytraumaを考慮しつつ,さまざまな透析手法に視野を広げた対応が試みられている。
Studies on acute kidney injury (AKI) with a variety of pathophysiological backgrounds are being conducted, and approaches to AKI different from the traditional prerenal/renal/postrenal classification are required. The characteristics of AKI in the intensive care unit and emergency room and the mechanisms and treatment methods for cardiorenal syndrome, septic AKI, cardiac surgery-associated AKI, hepatorenal syndrome, and abdominal compartment syndrome were reviewed. In all of these syndromes, hemodynamics, abnormalities in neurohumoral factors, inflammation, metabolism, and drugs are involved in a complex manner. Management using multiple approaches is necessary for treatment. In recent years, renal replacement therapy has been performed using various dialysis techniques, taking into account individual pathophysiology and dialytrauma.

Copyright © 2023, MEDICAL SCIENCES INTERNATIONAL, LTD. All rights reserved.