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Vasculitic emergencies in patients with medium and small vessel vasculitis Hiromichi TAMAKI 1 1Section of Allergy and Rheumatology Department of Internal Medicine St. Luke's International Hospital pp.957-966
Published Date 2018/10/1
DOI https://doi.org/10.11477/mf.3102200576
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Primary systemic vasculitides are categorized into three groups (large vessel, medium vessel and small vessel vasculitis) based on the size of most affected blood vessels as defined by the 2012 Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitides. Medium vessel vasculitides include Polyarteritis Nodosa and Kawasaki Disease. Small vessel vasculitides include Anti-neutrophil cytoplasmic antibody associated vasculitis (Microscopic Polyangiitis, Granulomatosis with polyangiitis [Wegener's], and Eosinophilic Granulomatosis with Polyangiits [Churg-Strauss]), Anti-glomerular basement membrane antibody (GBM) Disease, Cryoglobulinemic Vasculitis, IgA vasculitis (Henoch-Schönlein) and Hypocomplementemic Urticarial Vasculitis (Anti-C1q Vasculitis). These vasculitides can cause various medical emergencies due to ischemia or hemorrhage related to the vasculitis. In this review, a general approach to suspected vasculitis is presented. The clinical manifestations, differential diagnosis and management of three vasculitic emergencies including angiitis of the central nervous system, pulmonary renal syndrome, and intraabdominal hemorrhage due to Polyarteritis Nodosa are discussed and reviewed.


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電子版ISSN 2186-7852 印刷版ISSN 1883-4833 メディカル・サイエンス・インターナショナル

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