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pp.115-124
Published Date 1959/6/15
DOI https://doi.org/10.11477/mf.2425906074

 DNP produces the marked carbohydrate consumption associated with the stimulation of respiration in aerobic system in vitro, and these phenomena have been explained by the specific effect of the drug which interrupts the normal linkage of oxidation and phosphorylation.

 Although the responses to DNP in vivo are similar outwardly to those in vitro, we should rather consider the participation of some endocrine glands, especially adrenals.

 On the other hand, the fact that DNP is readily inactivated (reduction or conjugation) by living cells should be noted to discuss the mechanism of actions of DNP.


Copyright © 1959, THE ICHIRO KANEHARA FOUNDATION. All rights reserved.

基本情報

電子版ISSN 1883-5503 印刷版ISSN 0370-9531 金原一郎記念医学医療振興財団

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