Metallo-β-lactamase producing organisms Intetsu Kobayashi 1 1Department of Infection Control and Prevention, School of Nursing, Faculty of Medicine, Toho University Keyword: メタロ-β-ラクタマーゼ(MBL) , カルバペネマーゼ , ニューデリーメタロ-β-ラクタマーゼ1(NDM-1) , 腸内細菌 , ブドウ糖非発酵菌 pp.891-894
Published Date 2012/8/15
DOI https://doi.org/10.11477/mf.1542103102
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MBLs (metallo-β-lactamases) produced by gram negative bacteria are enzymes belonging to Ambler's class B that can hydrolyze carbapenems and a wide variety of β-lactams, Among them, class B MBLs have been identified in Pseudomonas aeruginosa and in several non-glucose-fermenters. In recent years a novel metallo-β-lactamase NDM-1 producing isolate of Enterobacteriaceae has been reported. In this section, I review and discuss the prevalence and types of MBL producers in the domestic sphere and in foreign countries and the future problems involved in NDM-1-producing bacteria.

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