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Multi-drug resistant tuberculosis Masao Okumura 1 , Takashi Yoshiyama 1 1Department of Respiratory Medicine, Fukujuji Hospital, Japan Anti-Tuberculosis Association Keyword: 多剤耐性結核症(MDR-TB) , man-made disease , 薬剤感受性検査 , 多剤併用化学療法 pp.895-899
Published Date 2012/8/15
DOI https://doi.org/10.11477/mf.1542103103
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MDR-TB (multi-drug resistant tuberculosis) is defined as tuberculosis that is resistant at least to INH (isoniazid) and RFP (rifampicin), the two powerful first-line anti-TB drugs. MDR-TB develops during treatment of fully sensitive TB when the course of antibiotics is interrupted and the levels of drug in the body are insufficient to kill 100% of bacteria. This can happen for a number of reasons : Patients may feel better and halt their antibiotics course, drug supplies may run out or become scarce, or patients may forget to take their medication from time to time. MDR-TB is spread from person to person as readily as drug-sensitive TB and in the same manner. MDR-TB is a man-made-disease. We need a drug sensitivity test to start treatment. Treatment results of MDR-TB are not satisfactory. But we need to prevent new MDR-TB cases.


Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

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