Rinsho Kensa Volume 56, Issue 8 (August 2012)

Extended-spectrum beta-lactamase producing bacteria Yumiko Kimura 1,2 , Katsunori Yanagihara 2 1Department of Clinical Laboratory, National Hospital Organization Nagasaki Medical Center 2Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences Keyword: ESBL , CTX-M型 , クラブラン酸 pp.884-890
Published Date 2012/8/15
DOI https://doi.org/10.11477/mf.1542103101
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ESBL, which is short for Extended -spectrum beta-lactamase, is capable of efficiently hydrolyzing penicillin-based antibiotic and oxyimino cephalosporin including ceftazidime and cefotaxime, and monobactam antibiotic. Especially to be noted is that the ESBL-producing gene produces the gram-negative rod of Enterobacteriaceae, and spreads various types of the bacterial strain, because the ESBL producing gene is a plasmid-derived gene. In recent years, the isolation frequency of ESBL producing bacteria has been drastically increasing around the world. To prevent the ESBL producing bacteria from spreading, there is an overriding importance to be attached to screening and detection of ESBL-producing bacteria. It should also be noted that we have to practice the proper use of antibiotics and increase infection control.

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56巻8号 (2012年8月)
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