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Omics : Contribution to clinical medicine through systems biology Tsutomu Nobori 1 1Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine Keyword: オミクス , オーム , システム生物学 pp.1113-1120
Published Date 2011/10/30
DOI https://doi.org/10.11477/mf.1542102791
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When the draft reference sequence of the human genome was reported in 2003, the first page of the post-genomic era was opened. The development of various omics technologies made the global and high-throughput analyses possible. Neologisms with the suffix "ome" such as genome, transcriptome, proteome, and so on, were created. For instance, the genome means the entire set of genetic instructions found in a cell, since "ome" is derived from the Sanskrit OM ("completeness and fullness"). Omics means to study the entire set of molecules, e. g. genes in genomics. In omics science, the process of research is fundamentally altered from the "first hypothesize-then-experiment" to "first experiment-then-hypothesize" approach. This kind of omics approach leads to biomarker discovery and personalized medicine through systems biology.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

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