Rinsho Kensa Volume 54, Issue 5 (May 2010)

Detection and clinical significance of multidrug-resistant organisms:metallo-β-lactamases producing bacteria Hiromu Takemura 1,2,3 1Department of Microbiology, St. Marianna-University School of Medicine 2Infection Control Team, St. Marianna-University Hospital 3St. Marianna-University Hospital Keyword: メタロ-β-ラクタマーゼ , カルバペネム薬耐性 , 多剤耐性緑膿菌 pp.513-518
Published Date 2010/5/15
DOI https://doi.org/10.11477/mf.1542102294
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Metallo-β-lactamases(MBLs)are the most clinical important carbapenemases and hydrolyze virtually all β-lactamases except the monobactam. Many kinds of MBL producing gram-negative bacilli have been detected in Japan, and IMP-1 producing Pseudomonas aeruginosa have dominated other strains. Cases of severe infectious disease, e.g. pneumonia and sepsis, with MBL producing bacteria are still rare in Japan, but, special attention is needed for them, because the causative bacteria might be resistant to all clinically applicable antibiotics.

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54巻5号 (2010年5月)
電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院