大阪大学における鼻アレルギーの現況（第5報）—RIST，RASTについて

Clinical Study of Nasal Allergy in Osaka University (Report No. 5)

I．はじめに

　最近鼻アレルギー診断のための検査は多様化しつつある。中でも血清総IgEの定量検査であるRISTが日常的に行われるようになり，また抗原検索の方法としてin vitroで行えるRASTが注目され，実用化されている。今回はこの血清IgEに関する2種の検査と臨床所見，とくに診断面との関連について統計的な観察を行い，興味ある結果を得たので報告する。

　RIST (serum IgE) was examined and RAST for quantitative estimation of IgE antibodies to 5 aeroallergens (Dermatophagoides, house dust, cedar, ragweed, Candida) in 100 patients with nasal allergy was studied. The results of RIST and RAST were compared with those of clinical studies of nasal allergy and the results demonstrated a decrease in serum IgE levels in accordance with aging. The patients with seasonal allergy showed the lower levels of serum IgE than those in nonseasonal ones. The frequency of positive RAST reactivity to Dermatophagoides and house dust was greater among younger people. The greatest frequency of positive RAST reactivity to cedar, ragweed and Candida was observed in those from 20 to 30 years of age. Good agreement was found between RAST and clinical diagnosis for cedar allergy.