- 有料閲覧
- 文献概要
- 1ページ目
I.緒言
無カタラーゼ血液症は血液および可検組織(鼻腔,咽頭,骨髄,穿刺肝組織)中にカタラーゼ酵素を欠如する稀な先天的体質異常で,1947年(昭和22年)高原教授によつて,初めて発見報告されたものである。その後,日本国内の各地より症例が追加され,現在迄18家系40例が報告されている。
我々は既に1957年に竹内が報告した無症状型無カタラーゼ血液症症例のM家系につき,更に詳しい家系調査を進めていた際,偶々2家系3症例の本症を発見し得たので報告する。
Fujimori et al report 3 cases of acatalasemia a blood condition which was first called attention to by Professor Takahara in 1947.Since then 2 more cases of similar conditions namely,asymptomatic acatalasemia were added to the list by Takeuchi in 1957.The present attempt is a study on family histories of these case including the ones reported by Takeuchi.
The 3 cases reported here were also asym-ptomatic.No blood relation existed in the parents of one case;the other two were siblings of the same parent who were second cousins to each other.
Conclusions from this study pointed to the fact that hypocatalsemia plays the role of carrier state to the development of acatal-asemia.
Copyright © 1962, Igaku-Shoin Ltd. All rights reserved.