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緒言
Streptomycinがその副作用として,屡々聴力障碍を招来する事は,衆知の事実であつて,その報告も種々の面から数多くなされて居るが,何れも主として発現した難聴の調査が主である様に考へられる。然し,Streptomycin難聴の発現を予防的見地から考慮するには,適当な対象群に対し,任意に注射されたStreptomycinに依り,如何なる様式に難聴が発現するかと云ふ事を研究する必要がある。
Moriyama and Yano maintain that the onset of deafness as a complication of streptomycin therapy may be made preventable by institut-ing periodic observations with audiograms after initiation of that therapy. They find that deafness manifested here is characterized by C6 dip or sudden fall of tones higher than that. Studies with audiograms were conducted among 80 patients who were under dihydro-streptomycin therapy by intramuscular injec-tions: 30 showed appreciable changes. Among this cases only 4 complained of subjective deaf-ness while the remaining 26 must be considered as deafness with latent symptoms as far as the patients were concerned.
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