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Psychiatric symptoms associated with thalamic lesions. Hideo TOHGI 1 , Toshiaki KONNO 1 , Kenichi CHIBA 1 , Yuichi NOZAKI 1 1Department of Neurology, Iwate Medical University pp.509-517
Published Date 1988/6/10
DOI https://doi.org/10.11477/mf.1431906204
  • Abstract
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Patients with thalamic lesions may present psychiatric symptoms such as disturbance of con-sciousness, attention, emotion, and motivation, akinetic mutism and dementia. Thalamic nuclei involved in such cases are,(1) those which have close connections with the association areas of the cerebral cortex such as dorsomedial nucleus and pulvinar, and (2) those which belong to the nonspecific (diffuse) projection system (intralaminar nucleus, midline nuclei, and reticular nucleus).

Although these nuclei have connections with wide areas of the cerebral cortex, the intensity of thalamic projections is different among cortical regions. Therefore, focal cortical symptoms may outstand amongst generalized mental deficits in patients with thalamic lesions. The frontal lobe, in particular, is closely related to the dorsomedial nucleus. Thus, patients with medial thalamic lesions often present symptoms resembling the frontal lobe syndrome, and show the decrease of cerebral blood flow in the frontal lobe.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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