雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Pathological Study of Toxic Polyneuropathy (Ⅰ): Experimental Formation of Polyneuropathy by Methylmercury Hideyo Matsumoto 1 , Nobue Tomio 1 , Takamasa Kameda 1 1Dept. of Pathology, Kumamoto Univ. School of Med pp.660-669
Published Date 1969/11/25
DOI https://doi.org/10.11477/mf.1431904632
  • Abstract
  • Look Inside

 Fifty-one adult and weanling rats have been administered per os with methylmercuric chloride and the resulting pattern of degeneration in peripheral nerves has been studied.

 Methylmercuric chloride can produce disturbance of the peripheral nerves at a dose of 5mg per day, totalling 40-60mg in three weeks.

 Histopathologically, methylmercuric chloride predominantly affects myelin sheath, while axon fibers are less damaged. The pattern of degeneration of myelin sheath is segmental demyelination. These disturbances begin to occur usually in Ranvier's node.


Copyright © 1969, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

関連文献

もっと見る

文献を共有