Japanese

The diagnosis for and pathogenesis of Bickerstaffs brainstem encephalitis Masaaki ODAKA 1 , Nobuhiro YUKI 1 1Department of Neurology, Dokkyo University School of Medicine Keyword: Bickerstaff型脳幹脳炎 , 先行感染因子 , Fisher症候群 , Guillain-Barré症候群 , IgG抗GQ1b抗体 pp.114-127
Published Date 1999/2/10
DOI https://doi.org/10.11477/mf.1431901031
  • Abstract
  • Look Inside

We examined a nosological position of Bickerstaff s brainstem encephalitis (BBE) as referring to original cases [Bickerstaff and Cloake (1951) ; Bickerstaff (1957)]. Patients, who show drowsiness, brisk reflexes, extensor plantar responses, hemisensory disturbance, cerebral hemisphere signs and Parkinsonism in addition to acute ophthalmoplegia and cerebellar ataxia, usually were diagnosed to have BBE rather than Fisher's syndrome. IgG anti-GQ1b antibody was detected in BBE, which suggests that this conditions are categorized as autoimmune diseases related to Fisher's syndrome. The symptoms of fever (92%), headache (33%), general malaise (33%) often preceded and a half of patients had a history of sore throat and cough before the onset of neurological symptoms. Cases of BBE were found associated with herpes simplex virus, Epstein-Barr virus, echo virus, adeno virus, Salmonella typhi, measles virus, cytomegalovirus, and Mycoplasma pneumoniae as antecedent infec-tious agents.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

関連文献

もっと見る

文献を共有