雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Probing the temporal dynamics of the functional system interaction in the brain by functional MRI Seiji Ogawa 1 , Yuruwan Son 1 , Masayuki Kanba 1 , Tsukasa Nagaoka 2 1Hamano Life Science Research Foundation, Ogawa Laboratories for Brain Function Research 2Albert Einstein College of Medicine, Yeshiva University Keyword: BOLD , 信号強度 , 機能抑制 , 不応現象 pp.902-908
Published Date 2003/12/10
DOI https://doi.org/10.11477/mf.1431100377
  • Abstract
  • Look Inside

 fMRI is known to be a method to find locations of sites in the brain which respond to a given functional task. The response time of fMRI signal, however, is at the order of seconds and too slow to detect any temporally fast neural process a functional system takes to perform a task. It is also well-known that fMRI signal is tightly coupled to such neural process and sensitive to show a change in signal amplitude when the neural system-activity changes. In rat models as well as in the human brain, we show that such signal changes responding to activity variation are observable even it occurs within 10's milliseconds or hundreds milliseconds. Using pair wise stimulation paradigms, we have examined these signal responses in MT to characterize some aspects of a neuro-refractory response. We pursue the potential of such approach to detect interaction among sites activated by performing some functional task.


Copyright © 2003, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

関連文献

もっと見る

文献を共有