BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 70, Issue 8 (August 2018)

Neuropathologic Aspects of Co-occurrence of Dementia with Lewy Bodies and Alzheimer's Disease Masaki Takao 1 1Department of Neurology, Saitama International Medical Center Keyword: 認知症 , レヴィ小体 , アルツハイマー病 , 神経病理 , dementia , Lewy body , Alzheimer's disease , neuropathology pp.905-913
Published Date 2018/8/1
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Dementia with Lewy bodies (DLB) is a clinically and neuropathologically defined syndrome and the second cause of dementia in elderly individuals. In addition to the presence of Lewy-related pathology (Lewy bodies and neurites), Alzheimer's disease(AD)-type neuropathologic changes such as senile plaques and neurofibrillary tangles are frequently present. In this review, the author focused on the co-occurrence of pathologic changes of DLB and AD. However, in order to understand recent concepts of dementia, clinicians need to realize that multiple brain pathologies are common in elderly patients.

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BRAIN and NERVE-神経研究の進歩
70巻8号 (2018年8月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院