BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 69, Issue 7 (July 2017)

Bioinformatics Analysis of Alzheimer's Disease Masataka Kikuchi 1 , Akihiro Nakaya 1 1Department of Genome Informatics, Graduate School of Medicine, Osaka University Keyword: バイオインフォマティクス , 全ゲノム関連分析 , マイクロアレイ , RNAシークエンス法 , ネットワーク解析 , bioinformatics , GWAS , microarray , RNA-seq , network analysis pp.835-842
Published Date 2017/7/1
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With the spread of microarray and next-generation sequencing technologies, massive amounts of data can be collected. However, these collections of data require the use of "big data" data-mining techniques to extract the relevant information. These techniques are applied to biological data through bioinformatics studies. By applying these bioinformatics approaches to various omics datasets, the complex pathology of Alzheimer's disease (AD) has been substantially revealed. In this paper, we focus on the genomics- and transcriptomics-based studies, and review previous AD studies using these newer bioinformatics approaches.

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BRAIN and NERVE-神経研究の進歩
69巻7号 (2017年7月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院