小児精巣ライディッヒ細胞腫の1例

TESTICULAR LEYDIG CELL TUMOR IN A CHILD

　6歳，男児。5歳頃より軽度の陰茎肥大，陰毛の発現，変声等の思春期早発症状を認め当院小児科受診。内分泌学的検査にて血中テストステロン，尿中17—ケトステロイドの異常高値。右精巣の腫大を認めたため，右精巣腫瘍疑い当科受診。諸検査の結果，ホルモン産生精巣腫瘍の診断にて右高位除睾術施行。術後，血中テストステロン，尿中17—ケトステロイド等は低下し正常範囲を示した。また，夢精，顔面の座瘡は消失したが，陰茎肥大，陰毛等の外性器所見および左精巣には変化を認めず，術後再発・転移も認めていない。

The patient was a 6-year-old boy who was brought to the pediatrics department for consultation regarding symptoms of precocious puberty. From the age of about 5 years, this child had shown slight enlargement of the penis, development of pubic hair, changing of the voice and other signs of puberty. Endocrinological studies revealed elevated serum testosterone and urinary 17-KS, while physical examination disclosed the enlarged right testis. A right testicular tumor was suspected and a high right orchiectomy was performed. Postoperatively, serum testosterone and urinary 17-KS fell to normal.