排尿障害を示したハンチントン舞踏病の1例

MANIFESTATION OF MICTIONAL DISTURBANCE IN HUNTINGTON'S CHOREA: A CASE REPORT

　ハンチントン舞踏病に排尿障害が認められた稀有なる症例について報告した。症例は42歳，男。主訴は排尿障害と排尿回数の減少。膀胱容量は800 ml以上で残尿は110 ml。膀胱内圧曲線はhypotonic bladderであり，外尿道括約筋筋電図は正常であつた。舞踏病様の不随意運動に一致してspike状の膀胱内圧の上昇と筋電図の振幅の増大が認められた。臭化ジスチグミンの投与で排尿状態は改善したが，膀胱内圧曲線には変化を認めなかつた。

A 42 year-old man with Huntington's chorea was admitted with complaints of dysuria and oligakiuria. His bladder had capacity of more than 800 ml and was hypotonic with normal activity of external ure-thral sphincter. According to choreiform movement, cystometrogram was showed spikes and electrogram of external urethral sphincter rapidly increased deflexions. Uroflowmetry showed a pattern of urinary difficulity. He was treated with distigmine bromide 5 mg three times a day.