昭和46年夏における伝染性膿痂疹の観察

STATISTIC STUDIES ON IMPETIGO CONTAGIOSUM IN THE SUMMER OF 1971

　伝染性膿痂疹は，夏季の幼小児の伝染性疾患としては最も多い疾患であるが，その特徴ある臨床症状より診断が容易であり，かつ比較的容易に治癒するため，その原因菌の検索や，その菌に対する薬剤感受性についてはなおざりにされる傾向が強く，治療方法も画一的になり勝ちである．しかしながら，その原因菌にも年次的変化や地域的差異があり，原因菌の薬剤感受性にも年々変化がみられる^1）．また最近，伝染性膿痂疹の遷延治癒等が原因となつて発症した膿痂疹性急性腎炎の報告が，欧米と同様に本邦においても散見されるようになつた^2,3,4）ことから考え，伝染性膿痂疹の治療に際してはこれらの続発症の問題も考慮されるべきであると考えられる．昨年われわれは，名古屋地区における夏季伝染性膿痂疹の原因菌と，その薬剤感受性とを検索する機会があつたので，その結果を報告するとともに，最近の伝染性膿痂疹の問題点につき若干の考察を行つてみたい．

Statistic studies on the causative bacteriae and their sensitivities to the drugs of 38 cases of the im-petigo contagiosum in the summer of 1971, in Nagoya City were performed.

Staph. aureus and staph. epidermidis were cultivated from 87 and 11% of these patients respectively.Drug sensitivity tests of the staph. aureus showed high sensitivity to cepharosporines, KM, TC, EM, andsynthetic penicillin for drugresistant staphylococcus, while high percentage of the bacteriae proved to beresistant to PC, AB-PC, or sulfonamides. Staph. epidermidis showed high sensitivity to cepharosporines,while some strain of the bacteriae showed resistance to the various kinds of antibiotics.

Considering on the results of sensitivity tests and concentability of the drugs, it seemed that for thetreatment of the impetigo in summer KM, TC, cepharosporins and EM would be proper. Furthermore inthe cases which do not react to macrorides, it is desirable to change drugs as soon as possible. It would be better to treat this disease as soon as possihile to avoid the possibility of th dangerous se-quences such as acute gromerulonephritis.