Jibi Inkoka, Tokeibu Geka Volume 68, Issue 10 (October 1996)

Flow Cytometric Analysis of DNA Content in Advanced Squamous Cell Carcinomas of the Head and Neck LiXin Zhou 1 1Department of Otorhinolaryngology, Yokohama City University, School of Medicine pp.872-877
Published Date 1996/10/20
DOI https://doi.org/10.11477/mf.1411901440
  • Abstract
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Cellular DNA contents of 72 advanced head and neck squamous cell carcinomas were examined. DNA aneuploidy was observed in 40 of 72 tumors (56%). The aneuploidy pattern was most frequent in hypopharyngeal carcinoma (83%), and laryn-geal carcinoma appeared to be the least one. There was no significant difference in DNA contents between the primary tumor and the metastatic lymph nodes. The survival rate was significantly lower in the cases with aneuploidy pattern than in those with diploid, especially in pharyngeal car-cinoma. Our results suggested that the DNA ploidy was the useful prognostic tool in head and neck carcinomas.

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68巻10号 (1996年10月)
電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院