Japanese

Two cases of second tumor following treatment for retinoblastoma Kumiko Nishiyama 1,4 , Takayoshi Kojima 2 , Kazuhiko Mishima 3 1Dept of Ophthalmol, Kawakita General Hosp 2Dept of Ophthalmol, Omiya Red Cross Hosp 3Dept of Neurosurg, Univ of Tokyo Sch of Med 4Dept of Ophthalmol, Tokyo Kyousai Hosp pp.1629-1634
Published Date 2001/9/15
DOI https://doi.org/10.11477/mf.1410907480
  • Abstract
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A 6-month-old female infant was diagnosed with bilateral retinoblastoma. Her left eye was enucleated.The right eye cured after photocoagulation, chemotherapy and irradiation totalling 40 Gy. Malignant fibrous histiocytoma developed in the left antrum 13 years later. It was successfully treated by surgical removal and irradiation. Another 3-month-old male infant was diagnosed with bilatelral retinoblastoma. His left eye was enucleated. The right eye cured after photocoagulation, chemotherapy and irradiation totalling 38 Gy. Meningioma developed 11 years later and was successfully treated by surgery. There has been no recurrence in both cases. The second tumor in both cases developed in irradiated areas. There is a possibility that irradiation as well as genetic factors may have been involved in its occurrence.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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