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Implication of serum immunosuppressive acidic protein in retinoblastoma Hiroshi Ikoma 1 , Takahiko Yokoyama 1 , Takayoshi Kojima 1 , Kensei Minoda 1 1Dept of Ophthalmol, Ichihara Hosp, Teikyo Univ, Sch of Med. pp.1225-1227
Published Date 1990/8/15
DOI https://doi.org/10.11477/mf.1410908230
  • Abstract
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We quantitated the serum level of immunosup-pressive acidic protein (IAP) in 9 patients with retinoblastoma before enucleation of eyeball and 2 weeks after. We correlated the findings with clini-cal and pathological data. Six cases showed normal IAP values of less than 500 μg/ml. Three cases showed definite high IAP values. These 3 caseswere characterized by the presence of additional clinical features as glaucoma or endophthalmitis. They were also unique as they were classified into T3c (choroidal invasion) or T4a (beyond lamina cribrosa) by TNM classification. The 6 cases with normal IAP value were pathologically classified into T3a or T3b. It appeared that serum IAP value in retinoblastoma was well correlated with the grade of tumor penetration.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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