Optical coherence tomography of retinal pigment epithelial detachment in age-related macular degeneration Taku Sato 1 , Tomohiro Iida 1 , Norikazu Hagimura 1 , Katsuya Suto 1 1Dept of Ophthalmol, Gunma Univ Sch of Med pp.152-157
Published Date 2001/2/15
DOI https://doi.org/10.11477/mf.1410907181
  • Abstract
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We examined age-related macular degeneration using an optical coherence tomography (OCT). Retinal pigment epithelial detachment (PED) was identified in 31 eyes. PED appeared as a dome-like elevation of highly reflective layer corresponding to the retinal pigment epithelium (RPE) and the choriocapillaris, with an optical clear space beneath the PRE. The PRE showed constriction, or a spatial notch sign, at the site of choroidal neovascularization (CNV) in 20 eyes. A high-reflective thick layer was present posterior and in ap-position to the detached RPE at the site of CNV in 11 eyes. The findings show that PED in age-related macular degeneration may manifest a spatial notch sign in addition to the classical one described by Gass. It appears that the spatial notch sign as seen by OCT is due to the presence of CNV adherent to the RPE and the choriocapillaris, and that it therefore suggests the presence of CNV.

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